Scientific writing has evolved into a standardised vehicle for the dissemination of research findings. The IMRAD, i.e. Introduction, Methods, Results, and Discussion format, is currently the dominant structure in biomedical publications. However, systematic principles governing scientific writing existed in antiquity. The concept of Tantraguna, described in the Charaka Samhita Vimanasthana, Sushrutsamhita Sutrasthana & Sahityadarpana, outlines essential qualities of an ideal scientific Shastra, including clarity, structure, conciseness, objectivity, authentication, and logical organisation. This review critically analyses Tantraguna and compares it with contemporary scientific writing frameworks, particularly IMRAD. The findings suggest that ancient Ayurvedic scholarship incorporated sophisticated methodological and epistemological standards parallel to modern academic norms. Integrating classical principles with contemporary guidelines may enhance the ethical, structural, and communicative quality of scientific writing. This narrative review analyses classical Ayurvedic textual descriptions of Tantraguna from the Vimanasthana of the Charaka Samhita and compares them conceptually with the modern IMRAD framework used in biomedical publications.